Abnormalities of taste sensation in cancer patients
نویسندگان
چکیده
منابع مشابه
Biochemical Studies of Taste Sensation
Large numbers of taste buds are distributed over the body surface of the channel catfish Zctalurus punctatus, with the barbels having an especially high density. L-Alanine, as well as certain other amino acids, are taste stimuli in this animal. Epithelial tissue obtained by gentle scraping of the barbel surface was fractionated by differential centrifugation. A sedimentable fraction (P2) was pr...
متن کاملHedgehog pathway blockade with the cancer drug LDE225 disrupts taste organs and taste sensation.
Taste sensation on the anterior tongue requires chorda tympani nerve function and connections with continuously renewing taste receptor cells. However, it is unclear which signaling pathways regulate the receptor cells to maintain chorda tympani sensation. Hedgehog (HH) signaling controls cell proliferation and differentiation in numerous tissues and is active in taste papillae and taste buds. ...
متن کاملIntravital Microscopic Interrogation of Peripheral Taste Sensation
Intravital microscopy is a powerful tool in neuroscience but has not been adapted to the taste sensory organ due to anatomical constraint. Here we developed an imaging window to facilitate microscopic access to the murine tongue in vivo. Real-time two-photon microscopy allowed the visualization of three-dimensional microanatomy of the intact tongue mucosa and functional activity of taste cells ...
متن کاملRapid Report Hedgehog pathway blockade with the cancer drug LDE225 disrupts taste organs and taste sensation
Archana Kumari,* Alexandre N. Ermilov,* Benjamin L. Allen,* Robert M. Bradley,* Andrzej A. Dlugosz,* and Charlotte M. Mistretta* Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan; Department of Dermatology, Medical School, University of Michigan, Ann Arbor, Michigan; Department of Molecular and Integrative Physiology, Medical School,...
متن کاملLiposomal treatment of xerostomia, odor, and taste abnormalities in patients with head and neck cancer.
BACKGROUND Smell and taste disorders, sicca symptoms, can be detected in patients with head and neck cancer. The purpose of this study was to assess the utility of local liposomal application in the treatment of patients with head and neck cancers. METHODS Ninety-eight patients with head and neck cancer were included in this study. The groups were defined as: group 1 = only surgery; group 2 =...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer
سال: 1975
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197511)36:5<1888::aid-cncr2820360546>3.0.co;2-y